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This thesis explores how Wilkie Collins’s portrayal of disabled female bodies disrupts the Victorian opposition between ‘normal’ and ‘abnormal’ bodies, and, in doing so, offers an alternative to the prevailing contemporary ideal of femininity, as…

Obesity results when energy intake chronically exceeds energy expenditure, driving accumulation and malfunctioning of white adipose tissue and increasing risk for comorbidity. Brown adipose tissue (BAT) burns energy via adaptive thermogenesis, a…

Obesity is a disease that occurs when energy intake exceeds energy expenditure, concomitantly increasing risk of chronic diseases, including metabolic diseases such as diabetes. Research into therapeutics to correct dysregulations in energy balance…

Global ecosystems are increasingly affected by climate change leading to alterations in expected disturbance regimes. Outbreaks of irruptive insect pests represent some of the most destructive disturbance events possible that occur in the forests of…

Rapid urbanization has led to an increasing demand for sustainable living and working spaces. In response, renewable materials like wood, especially in the form of Cross-laminated timber (CLT), have gained traction due to their sustainability, cost-…

Phytoplankton bloom has become a growing global concern in recent years due to the excessive growth of algae, causing significant negative impacts on aquatic ecosystem and threatening human health. Growing evidence suggests that algal blooms are a…

Small molecules, including synthetic and those isolated from natural products, are important classes of compounds with broad utility, including drugs. The objectives of this dissertation were (i) to synthesize, purify, and characterize novel small…