This research sought to explore the perceptions of health and well-being for women in a rural and remote northeastern British Columbia community experiencing intense social, ecological, and economic change as a result of its dependence on natural resource extraction. Designed as a qualitative inquiry into the health of local women, this research is informed by social constructivism, feminist theory, and ecosystems approaches to health. Engagement with participants and data collection was heavily influenced by Appreciative Inquiry, a strengths-based approach that identifies assets within a given system with the aim of contributing to positive change. Findings indicate that equitable access, perceptions of people and place, and leadership, communication, and collaboration are factors that strongly impact women’s health and in this context.