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The role of pituitary adenylate cyclase-activating polypeptide (PACAP) in the ventromedial nucleus and its association with the melanocortin system in regulating adaptive thermogenesis
Digital Document
The role of pituitary adenylate cyclase-activating polypeptide (PACAP) in the ventromedial nucleus and its association with the melanocortin system in regulating adaptive thermogenesis
Towards an understanding of the management of pine-lichen woodlands in the Omineca region of British Columbia.
Digital Document
Towards an understanding of the management of pine-lichen woodlands in the Omineca region of British Columbia.
Perceived barriers and meanings: The experiences of people accessing northern mental health services.
Digital Document
Perceived barriers and meanings: The experiences of people accessing northern mental health services.
Adolescence and depression: reducing cardiovascular disease through preventive health checks
Digital Document
Adolescence and depression: reducing cardiovascular disease through preventive health checks
Assessment of LiDAR snow depth measurements and the spatiotemporal variability of the snowpack in a forested watershed on Vancouver Island
Digital Document
Assessment of LiDAR snow depth measurements and the spatiotemporal variability of the snowpack in a forested watershed on Vancouver Island
Mindfulness and the primary care provider
Digital Document
Mindfulness and the primary care provider
Primary care providers (PCPs), including nurse practitioners and primary care physicians, experience significant occupational stress, putting them at risk for chronic stress and burnout. Burnout rates are high amongst PCPs, and results in negative…
Patient reported-outcome measures of quality of life as a communication tool for primary care providers serving caregivers of adults with cancer
Digital Document
Patient reported-outcome measures of quality of life as a communication tool for primary care providers serving caregivers of adults with cancer
An agent-based model for evolution of cooperation with proactive information gathering
Digital Document
An agent-based model for evolution of cooperation with proactive information gathering
Machine learning based classification of early seral vegetation in cut-blocks in the interior of northern British Columbia
Digital Document
Machine learning based classification of early seral vegetation in cut-blocks in the interior of northern British Columbia
Spiropyrrolizidine and piperazine derivatives: Synthesis and evaluation on kras expression levels in human colon cancer cells
Digital Document
Spiropyrrolizidine and piperazine derivatives: Synthesis and evaluation on kras expression levels in human colon cancer cells
KRAS-driven cancers are notoriously difficult to treat due to poor pharmacodynamics of downstream inhibitors and resistance to anti-EGFR drugs. IMP-1 is a post-transcriptional regulator of KRAS mRNA. As a novel therapeutic approach, the targeting of…
Population monitoring and community support for hog deer (Axis porcinus) conservation in Shuklaphanta National Park, Nepal
Digital Document
Population monitoring and community support for hog deer (Axis porcinus) conservation in Shuklaphanta National Park, Nepal
Precipitation gradients across the Continental Divide in the southern Canadian Rockies
Digital Document
Precipitation gradients across the Continental Divide in the southern Canadian Rockies
This project examines precipitation patterns across the Continental Divide in the southern Canadian Rockies with a focus on precipitation gradients. This thesis is part of the Storms and Precipitation Across the continental Divide Experiment (SPADE…
Purification and characterization of an immuno-stimulatory compound from the water extract of royoporus badius (Pers.) A.B. De
Digital Document
Purification and characterization of an immuno-stimulatory compound from the water extract of royoporus badius (Pers.) A.B. De
Investigation of microbubbles and nanobubbles gas flotation for oil separation from marine oily wastewater using response surface methodology
Digital Document
Investigation of microbubbles and nanobubbles gas flotation for oil separation from marine oily wastewater using response surface methodology
Oily wastewater caused by marine oil spills brings great harm to the environment. In this work, the application of gas flotation with microbubbles and nanobubbles in separating crude oil droplets from oily wastewater is reported. The experiments…
Reduce obesogenic environments for children: the role of nurse practitioners in community-oriented primary care
Digital Document
Reduce obesogenic environments for children: the role of nurse practitioners in community-oriented primary care
Point-of-care ultrasound education needs for nurse practitioners in primary care settings: An integrative review
Digital Document
Point-of-care ultrasound education needs for nurse practitioners in primary care settings: An integrative review
Point-of-care ultrasonography (POCUS) is the process of operating a compact ultrasound machine at a patient’s location and immediately integrating the images generated into patient care. POCUS can help nurse practitioners (NPs) make more accurate…
Late Holocene Glacier fluctuations in southernmost Patagonia.
Digital Document
Late Holocene Glacier fluctuations in southernmost Patagonia.
A framework for mapping cumulative threats and its application to Canada
Digital Document
A framework for mapping cumulative threats and its application to Canada
Methods for cumulative threat mapping, such as the human footprint, have been rapidly developing to inform the management of biodiversity and ecosystem services. Here, I perform the first comprehensive literature review establishing what methods are…
Experimental approach to overexpress pituitary adenylate cyclase activating polypeptide (PACAP) specifically in the hypothalamus
Digital Document
Experimental approach to overexpress pituitary adenylate cyclase activating polypeptide (PACAP) specifically in the hypothalamus
Obesity is adetrimental health condition that occurs when energy intake, exceeds energy expenditure. Pituitary adenylatecyclase-activating polypeptide (PACAP) regulates energy expenditure, including adaptive thermogenesis, through the hypothalamic-…
Purification and characterization of growth-inhibitory compounds from 2 genera of British Columbia wild mushrooms: fomitopsis and phaeolus
Digital Document
Purification and characterization of growth-inhibitory compounds from 2 genera of British Columbia wild mushrooms: fomitopsis and phaeolus
Modern science is currently working to characterize the beneficial compounds from mushrooms and their potential as pharmaceutical drugs. In this thesis, eight British Columbian wild mushroom collections (3 species), comprising Fomitopsis pinicola,…
In search of novel immune-modulatory compounds from British Columbia wild mushrooms and their effectiveness in inflammatory micro-circulation of mice
Digital Document
In search of novel immune-modulatory compounds from British Columbia wild mushrooms and their effectiveness in inflammatory micro-circulation of mice
Improving Sonar Sensor Fidelity in a Robot Simulator.
Digital Document
Improving Sonar Sensor Fidelity in a Robot Simulator.
Phosphorus distribution with respect to particle size and microbial activity in dairy manure and implications for manure management
Digital Document
Phosphorus distribution with respect to particle size and microbial activity in dairy manure and implications for manure management
This work investigated the distribution of phosphorus in dairy manure as it relates to particle size and provides experimentally derived insights for improving the management of phosphorus. The data presented here illustrates some aspects of manure…
Interval-valued Pythagorean fuzzy decision-making models for evaluating challenges of digital transformation
Digital Document
Interval-valued Pythagorean fuzzy decision-making models for evaluating challenges of digital transformation
The aim and objective of the thesis entitled “Interval-valued Pythagorean Fuzzy Decision-Making Models for Evaluating Challenges of Digital Transformation” are as follows: The first objective is to develop new entropy and divergence measures to…
Glacier change and contribution to streamflow in the Canoe Basin, British Columbia, 1948-2005.
Digital Document
Glacier change and contribution to streamflow in the Canoe Basin, British Columbia, 1948-2005.