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Research Paper Project OR Dissertation Thesis
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Inhibition of pre-mRNA splicing by small molecules.
Dissection of U4 snRNA functional domains using in vitro reconstitution.
Characterization of a novel endoribonuclease capable of degrading c-myc mRNA in vitro.
Evaluation of potassium stress responses and identification of novel RT-qPCR reference genes in the haloarchaeon, Haloarcula marismortui .
Investigation into class II P-glycoprotein messenger RNA decay in normal liver and liver tumours.
RNA sequences and structures cleaved by a novel mammalian endoribonuclease in vitro.
Synthesis of Spirolactones Substituted at the Benzylic Position: Studies Toward the Formation of Manumycin Structural Analogs.
Isolation and characterization of the U4 snRNP in Saccharomyces cerevisiae.
Diastereoselective spiroannulation of phenolic derivatives: Effect of steric hindrance on the diastereoselectivity.
Studies towards the diastereoselective formation of the manumycin m-C(7)N core.
Structure Probing of U4 snRNA: Investigations into the Mechanism of U4/U6 di-snRNP Formation.
Purification, identification and characterization of mammalian endoribonucleases that degrade c-myc mRNA in vitro.
Biochemical and cellular characterization of the coding region determinant-binding protein (CRD-BP)-mRNA interaction.
Chemical synthesis of two repeat units corresponding to the backbone of the pectic polysaccharide Rhamnogalacturonan I.
Towards identifying New Human Ribonucleases that Cleave microRNA Using a High-Throughput Method.
U6 snRNA secondary structure in free U6 snRNPs.
Assessing Rattus norvegicus recombinant syntaxin 18 for endonucleolytic function.
Characterizing the CRD-BP-RNA interaction in-vitro and in cells.
The coding region determinant binding protein shields c-myc coding region determinant and MDR-1 RNAs from endonucleolytic attack by a novel mammalian endoribonuclease in vitro.
Identification and Validation of the U2, U4, U5, and U6 Spliceosomal snRNAs in Cyanidioschyzon merolae.
Investigating the 3' RNA Phosphodiesterase and 3'-5' Exoribonuclease Activities of APE1.
Use of pulp and paper sludge to improve performance of topsoil layer in a landfill capping system.
Assessing the role of Syntaxin18 in controlling c-myc mRNA expression and growth in human breast cancer cells.
Quasiclassical trajectory study of D+HH and H+HD.